Anti-Human CD43 Recombinant Antibody (SAA0015) (HB263107)

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货号	HB263107
品牌	abinScience
种属反应性	Human
应用	FCM
同种型	IgG1, kappa
克隆号	SAA0015
靶标	GPL115, Leukocyte sialoglycoprotein, Leukosialin, Sialophorin, SPN, Galactoglycoprotein, CD43, CD43ct, CD43-ct, GALGP
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P16150
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Leukosialin (CD43/SPN) is a ~40 kDa protein. Predominant cell surface sialoprotein of leukocytes which regulates multiple T-cell functions, including T-cell activation, proliferation, differentiation, trafficking and migration. Positively regulates T-cell trafficking to lymph-nodes via its association with ERM proteins (EZR, RDX and MSN). Negatively regulates Th2 cell differentiation and predisposes the differentiation of T-cells towards a Th1 lineage commitment. Promotes the expression of IFN-gamma by T-cells during T-cell receptor (TCR) activation of naive cells and induces the expression of IFN-gamma by CD4(+) T-cells and to a lesser extent by CD8(+) T-cells. Plays a role in preparing T-cells for cytokine sensing and differentiation into effector cells by inducing the expression of cytokine receptors IFNGR and IL4R, promoting IFNGR and IL4R signaling and by mediating the clustering of IFNGR with TCR. 1. Ramírez-Pliego, O. et al. (2007) BMC immunology 8, 30. PMID: 18036228 2. Galindo-Albarrán, AO. et al. (2014) Journal of cellular physiology 229, 172-80. PMID: 24328034
Note	For research use only.

Bioactivity

SEC-HPLC detection for Anti-Human CD43/SPN Antibody (ABS0999).
SDS-PAGE

SDS-PAGE for Anti-Human CD43 Recombinant Antibody (SAA0015)

产品说明书

Anti-Human CD43 Recombinant Antibody (SAA0015).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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C₁ × V₁ = C₂ × V₂

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C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

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Anti-Human CD43 Recombinant Antibody (SAA0015) (HB263107)

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Anti-Human CD43 Recombinant Antibody (SAA0015) (HB263107)

概述

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参考文献

产品说明书

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