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Anti-Mouse PrPC Recombinant Antibody (POM1) (MY392307)

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规格:
  • 50ug
  • 100ug
数量:
  • 概述

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  • 参考文献

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概述
货号MY392307
品牌abinScience
种属反应性Human, Mouse, Bovine, Hamster
应用ELISA, FCM
同种型IgG2a, kappa
克隆号POM1
经测试应用WB
靶标Major prion protein, PrP, PrP27-30, PrP33-35C, CD230, Prnp, Prn-p
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P04925
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Major prion protein (CD230/PRNP) is a ~27 kDa protein. Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis.

1. Mani, K. et al. (2003) The Journal of biological chemistry 278, 38956-65. PMID: 12732622
2. Steele, AD. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 3416-21. PMID: 16492732
3. Laurén, J. et al. (2009) Nature 457, 1128-32. PMID: 19242475
4. Singh, A. et al. (2009) PloS one 4, e6115. PMID: 19568430
NoteFor research use only.
图片
  • Bioactivity

    Detects Human CD230/PRNP in indirect ELISAs.

  • Western blot

    Western blot analysis was performed using anti-CD230/PRNP monoclonal antibody at 1ug/mL on various samples.
    Lane 1: recombinant human CD230/PRNP (Catalog No: HY392011)
    Lane 2: negative control

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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