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Anti-Human CCL5/RANTES Recombinant Antibody (SAA0456) (HY346107)

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  • 100ug
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  • 参考文献

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概述
货号HY346107
品牌abinScience
种属反应性Human
应用ELISA, FCM, WB
同种型IgG2a
克隆号SAA0456
靶标TCP228, C-C motif chemokine 5, CCL5, T cell-specific protein P228, D17S136E, Small-inducible cytokine A5, SIS-delta, SCYA5, T-cell-specific protein RANTES, Eosinophil chemotactic cytokine, EoCP
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P13501
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 0.09% Sodium azide.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

C-C motif chemokine 5 (CCL5/RANTES) is a ~9 kDa protein. Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).

1. Kameyoshi, Y. et al. (1992) The Journal of experimental medicine 176, 587-92. PMID: 1380064
2. Lim, JK. et al. (2005) Journal of leukocyte biology 78, 442-52. PMID: 15923218
3. Capoulade-Métay, C. et al. (2006) Immunogenetics 58, 533-41. PMID: 16791620
4. Cocchi, F. et al. (1995) Science (New York, N.Y.) 270, 1811-5. PMID: 8525373
5. Proost, P. et al. (1998) The Journal of biological chemistry 273, 7222-7. PMID: 9516414
6. Liu, B. et al. (2013) Diabetologia 56, 2467-76. PMID: 23979485
NoteFor research use only.
图片
  • Western blot

    Western blot analysis was performed using anti-CCL5/RANTES monoclonal antibody at 1ug/mL on various samples.
    Lane 1: recombinant human CCL5/RANTES (Catalog No: HY346012)
    Lane 2: negative control

  • Bioactivity

    Detects recombinant human CCL5/RANTES (Catalog No: HY346012) in indirect ELISA

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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