

| 货号 | HT305107 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Human |
| 应用 | ELISA, FCM, WB |
| 同种型 | IgG2a, kappa |
| 克隆号 | SAA0509 |
| 靶标 | CPER, CLDN4, Williams-Beuren syndrome chromosomal region 8 protein, CPE-R, CPE-receptor, WBSCR8, Claudin 4, Clostridium perfringens enterotoxin receptor, CPETR1 |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | O14493 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 0.09% Sodium azide. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 背景 | Claudin-4 (CLDN4) is a ~22 kDa protein. Can associate with other claudins to regulate tight junction structural and functional strand dynamics. May coassemble with CLDN8 into tight junction strands containing anion-selective channels that convey paracellular chloride permeability in renal collecting ducts. May integrate into CLDN3 strands to modulate localized tight junction barrier properties. May disrupt strand assembly of channel-forming CLDN2 and CLDN15 and inhibit cation conductance. Cannot form tight junction strands on its own. 1. Shashikanth, N. et al. (2022) Nature communications 13, 3780. PMID: 35773259 2. Gonschior, H. et al. (2022) Nature communications 13, 4985. PMID: 36008380 |
| Note | For research use only. |

SDS-PAGE for Anti-Human CLDN4/Claudin-4 Antibody (SAA0509)



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