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Anti-Human CLDN4/Claudin-4 Recombinant Antibody (SAA0509) (HT305107)

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概述
货号HT305107
品牌abinScience
种属反应性Human
应用ELISA, FCM, WB
同种型IgG2a, kappa
克隆号SAA0509
靶标CPER, CLDN4, Williams-Beuren syndrome chromosomal region 8 protein, CPE-R, CPE-receptor, WBSCR8, Claudin 4, Clostridium perfringens enterotoxin receptor, CPETR1
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号O14493
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 0.09% Sodium azide.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Claudin-4 (CLDN4) is a ~22 kDa protein. Can associate with other claudins to regulate tight junction structural and functional strand dynamics. May coassemble with CLDN8 into tight junction strands containing anion-selective channels that convey paracellular chloride permeability in renal collecting ducts. May integrate into CLDN3 strands to modulate localized tight junction barrier properties. May disrupt strand assembly of channel-forming CLDN2 and CLDN15 and inhibit cation conductance. Cannot form tight junction strands on its own.

1. Shashikanth, N. et al. (2022) Nature communications 13, 3780. PMID: 35773259
2. Gonschior, H. et al. (2022) Nature communications 13, 4985. PMID: 36008380
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human CLDN4/Claudin-4 Antibody (SAA0509)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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