Anti-Human GPC1 Recombinant Antibody (SAA0530) (HW614107)

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货号	HW614107
品牌	abinScience
种属反应性	Human
应用	ELISA, FCM
同种型	IgG1, kappa
克隆号	SAA0530
靶标	Glypican-1, GPC1
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P35052
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.09% Sodium azide. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Glypican-1 (GPC1) is a ~61 kDa protein. Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination. May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling.
Note	For research use only.

Flow Cytometry

Flow-cytometry using anti-human GPC1 antibody.A431 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human GPC1 antibody monoclonal antibody (Catalog # HW614107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody (Catalog # HF690414) and cells analysed on a NovoCyte Flow Cytometer.

产品说明书

Anti-Human GPC1 Recombinant Antibody (SAA0530).pdf

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Anti-Human GPC1 Recombinant Antibody (SAA0530) (HW614107)

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Anti-Human GPC1 Recombinant Antibody (SAA0530) (HW614107)

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参考文献

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