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Anti-Human C3AR1 Recombinant Antibody (SAA0776) (HS803107)

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规格:
  • 50ug
  • 100ug
数量:
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  • 参考文献

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概述
货号HS803107
品牌abinScience
种属反应性Human
应用ELISA, FCM
同种型IgG2a
克隆号SAA0776
靶标AZ3B, HNFAG09, C3AR1, C3R1, C3a-R, C3a anaphylatoxin chemotactic receptor, C3AR
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q16581
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 0.09% Sodium azide.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

C3a anaphylatoxin chemotactic receptor (C3AR1) is a ~53 kDa protein. Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a, stimulating chemotaxis, granule enzyme release and superoxide anion production. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. C3AR1 is coupled to G(i)/G(o) (GNAI1 or GNAO1) G alpha proteins and mediates inhibition of adenylate cyclase.

1. Gao, J. et al. (2003) The Journal of biological chemistry 278, 37902-8. PMID: 12871936
2. Yadav, MK. et al. (2023) Cell 186, 4956-4973.e21. PMID: 37852260
3. Ames, RS. et al. (1996) The Journal of biological chemistry 271, 20231-4. PMID: 8702752
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human C3AR1 Antibody (SAA0776)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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