Anti-Human DDR1 Recombinant Antibody (SAA0826) (HC282307)

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货号	HC282307
品牌	abinScience
种属反应性	Human
应用	ELISA, FCM
同种型	IgG1, kappa
克隆号	SAA0826
经测试应用	FCM
靶标	Protein-tyrosine kinase RTK-6, Protein-tyrosine kinase 3A, NTRK4, EDDR1, CAK, Tyrosine kinase DDR, Mammary carcinoma kinase 10, TRKE, Epithelial discoidin domain-containing receptor 1, CD167a, TRK E, Epithelial discoidin domain receptor 1, HGK2, CD167 antigen-like family member A, NEP, MCK-10, Tyrosine-protein kinase CAK, PTK3A, DDR1, Discoidin receptor tyrosine kinase, RTK6, Cell adhesion kinase
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	Q08345
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.09% Sodium azide. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Epithelial discoidin domain-containing receptor 1 (CD167a/DDR1) is a ~101 kDa protein. Tyrosine kinase that functions as a cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing.
Note	For research use only.

Bioactivity

Detects CD167a/DDR1 in indirect ELISAs.
Flow Cytometry

Flow-cytometry using anti-human CD167a antibody.CD167a Transfected CHO cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD167a antibody monoclonal antibody (Catalog # HC282307 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.

产品说明书

Anti-Human DDR1 Recombinant Antibody (SAA0826).pdf

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Anti-Human DDR1 Recombinant Antibody (SAA0826) (HC282307)

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Anti-Human DDR1 Recombinant Antibody (SAA0826) (HC282307)

概述

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参考文献

产品说明书

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