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Anti-Human BCMA/TNFRSF17 Recombinant Antibody (SAA0816) (HX959207)

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概述
货号HX959207
品牌abinScience
种属反应性Human
应用FCM
宿主Human
克隆类型Monoclonal
同种型IgG2, kappa
克隆号SAA0816
经测试应用FCM
靶标B-cell maturation protein, BCM, BCMA, CD269, TNFRSF17, Tumor necrosis factor receptor superfamily member 17
内毒素水平< 10 EU/mg
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q02223
状态Liquid
保存溶液 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Tumor necrosis factor receptor superfamily member 17 (CD269/BCMA) is a ~20 kDa protein. Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. CD269 is the therapeutic target of teclistamab (Tecvayli).

NoteFor research use only.
图片
  • Bioactivity

    SEC-HPLC detection for Anti-Human CD269/TNFRSF17/BCMA Antibody (ABS1826).

  • Flow Cytometry

    Flow-cytometry using anti-human CD269 antibody.CD269 Transfected CHO cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD269 antibody monoclonal antibody (Catalog # HX959207 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody (Catalog # HF690414) and cells analysed on a NovoCyte Flow Cytometer.

  • Flow CytoMetry

    Flow-cytometry using anti-human CD269 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human CD269 monoclonal antibody (Catalog: HX959207) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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