Anti-Canine CD28 Recombinant Antibody (1C6) (CY422107)

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货号	CY422107
品牌	abinScience
种属反应性	Canine
应用	ELISA, FCM
同种型	IgG2a, kappa
克隆号	1C6
靶标	CD28, TP44, T-cell-specific surface glycoprotein CD28
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	Q9N0N8
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.09% Sodium azide. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	T-cell-specific surface glycoprotein CD28 is a ~25 kDa protein. Receptor that plays a role in T-cell activation, proliferation, survival and the maintenance of immune homeostasis. Functions not only as an amplifier of TCR signals but delivers unique signals that control intracellular biochemical events that alter the gene expression program of T-cells. Stimulation upon engagement of its cognate ligands CD80 or CD86 increases proliferation and expression of various cytokines in particular IL2 production in both CD4(+) and CD8(+) T-cell subsets. Mechanistically, ligation induces recruitment of protein kinase C-theta/PRKCQ and GRB2 leading to NF-kappa-B activation via both PI3K/Akt-dependent and -independent pathways. In conjunction with TCR/CD3 ligation and CD40L costimulation, enhances the production of IL4 and IL10 in T-cells.
Note	For research use only.

SDS-PAGE

SDS-PAGE for Anti-Dog CD28 Antibody (1C6)

产品说明书

Anti-Canine CD28 Recombinant Antibody (1C6).pdf

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Anti-Canine CD28 Recombinant Antibody (1C6) (CY422107)

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实验相关试剂

Anti-Canine CD28 Recombinant Antibody (1C6) (CY422107)

概述

图片

参考文献

产品说明书

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