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Anti-Human CD148 Recombinant Antibody (AB-2) (HC363107)

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概述
货号HC363107
品牌abinScience
种属反应性Human
应用FCM
同种型IgG1, kappa
克隆号AB-2
靶标HPTP eta, R-PTP-J, Protein-tyrosine phosphatase eta, Density-enhanced phosphatase 1, Receptor-type tyrosine-protein phosphatase eta, Protein-tyrosine phosphatase receptor type J, DEP-1, R-PTP-eta, CD148, PTPRJ, DEP1
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q12913
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 0.09% Sodium azide.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Receptor-type tyrosine-protein phosphatase eta (CD148/PTPRJ) is a ~145 kDa protein. Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1, FLT3, PDGFRB, MET, KDR, LYN, SRC, MAPK1, MAPK3, EGFR, TJP1, OCLN, PIK3R1 and PIK3R2. Plays a role in cell adhesion, migration, proliferation and differentiation. Has a role in megakaryocytes and platelet formation. Involved in vascular development. Regulator of macrophage adhesion and spreading.

1. Kovalenko, M. et al. (2000) The Journal of biological chemistry 275, 16219-26. PMID: 10821867
2. Persson, C. et al. (2002) FEBS letters 517, 27-31. PMID: 12062403
3. Holsinger, LJ. et al. (2002) Oncogene 21, 7067-76. PMID: 12370829
4. Palka, HL. et al. (2003) The Journal of biological chemistry 278, 5728-35. PMID: 12475979
5. Tsuboi, N. et al. (2008) The Biochemical journal 413, 193-200. PMID: 18348712
6. Sacco, F. et al. (2009) The Journal of biological chemistry 284, 22048-22058. PMID: 19494114
7. Omerovic, J. et al. (2010) The Biochemical journal 426, 65-72. PMID: 19922411
8. Arora, D. et al. (2011) The Journal of biological chemistry 286, 10918-29. PMID: 21262971
9. Kellie, S. et al. (2004) Journal of cell science 117, 609-18. PMID: 14709717
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human CD148 Antibody (AB-2)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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