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Anti-Human TMEFF1 Recombinant Antibody (30C10) (HP664107)

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概述
货号HP664107
品牌abinScience
种属反应性Human
应用ELISA, FCM
同种型IgG2a, kappa
克隆号30C10
靶标C9orf2, H7365, TMEFF1, TR-1, Transmembrane protein with EGF-like and one follistatin-like domain, Tomoregulin-1
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q8IYR6
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Tomoregulin-1 (TMEFF1) is a ~40 kDa protein. Neuron-specific restriction factor that prevents herpes simplex virus 1 (HHV-1) infection in the brain by blocking viral entry. Also able to restrict herpes simplex virus 2 (HHV-2) infection, although to a lesser extent. Acts by preventing the association between the viral glycoprotein D (gD) and its cell surface receptor NECTIN1, thereby inhibiting fusion of the virus and the cell membrane. Also able to prevent the association between the viral glycoprotein B (gB) and MYH9/NMMHC-IIA and MYH10/NMMHC-IIB receptors. May be a tumor suppressor in brain cancers.

1. Dai, Y. et al. (2024) Nature 632, 383-389. PMID: 39048823
2. Chan, YH. et al. (2024) Nature 632, 390-400. PMID: 39048830
3. Gery, S. et al. (2003) Oncogene 22, 2723-7. PMID: 12743596
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human TMEFF1 Antibody (30C10)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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