Anti-Human CLDN1/Claudin-1 Recombinant Antibody (6F6C3) (HF976107)

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货号	HF976107
品牌	abinScience
种属反应性	Human
应用	ELISA, FCM
同种型	IgG2a, kappa
克隆号	6F6C3
靶标	CLDN1, Senescence-associated epithelial membrane protein, CLD1, Claudin 1, SEMP1
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	O95832
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Claudin-1 (CLDN1) is a ~22 kDa protein. Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an indirect effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions. 1. Kirschner, N. et al. (2013) The Journal of investigative dermatology 133, 1161-9. PMID: 23407391
Note	For research use only.

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SDS-PAGE for Anti-Human CLDN1/Claudin-1 Antibody (6F6C3)

产品说明书

Anti-Human CLDN1/Claudin-1 Recombinant Antibody (6F6C3).pdf

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Anti-Human CLDN1/Claudin-1 Recombinant Antibody (6F6C3) (HF976107)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CLDN1/Claudin-1 Recombinant Antibody (6F6C3) (HF976107)

概述

图片

参考文献

产品说明书

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