Anti-Human Neuropilin-1/NRP1 Recombinant Antibody (SAA0097), FITC (HT070117)

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货号	HT070117
品牌	abinScience
种属反应性	Human
应用	FCM
宿主	Human
同种型	IgG1, kappa
克隆号	SAA0097
偶联物	FITC
克隆类型	Monoclonal
靶标	NRP1, Neuropilin-1, VEGF165R, NRP, CD304, Vascular endothelial cell growth factor 165 receptor
内毒素水平	Please contact with the lab for this information.
相关产品	Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), FITC
Accession号	O14786
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Neuropilin-1 (CD304/NRP1) is a ~103 kDa protein. Cell-surface receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. Mediates the chemorepulsant activity of semaphorins. Recognizes a C-end rule (CendR) motif R/KXXR/K on its ligands which causes cellular internalization and vascular leakage. It binds to semaphorin 3A, the PLGF-2 isoform of PGF, the VEGF165 isoform of VEGFA and VEGFB. Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis. 1. Gagnon, ML. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 2573-8. PMID: 10688880 2. He, Z. et al. (1997) Cell 90, 739-51. PMID: 9288753 3. Soker, S. et al. (1998) Cell 92, 735-45. PMID: 9529250 4. Teesalu, T. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 16157-62. PMID: 19805273 5. Issitt, T. et al. (2019) iScience 11, 205-223. PMID: 30623799
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

产品说明书

Anti-Human Neuropilin-1/NRP1 Recombinant Antibody (SAA0097), FITC.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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C₁ × V₁ = C₂ × V₂

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Anti-Human Neuropilin-1/NRP1 Recombinant Antibody (SAA0097), FITC (HT070117)

概述

图片

参考文献

产品说明书

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重组蛋白

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试剂盒

实验相关试剂

Anti-Human Neuropilin-1/NRP1 Recombinant Antibody (SAA0097), FITC (HT070117)

概述

图片

参考文献

产品说明书

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