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Anti-Human LPL/LIPD Recombinant Antibody (5D2), FITC (HY363117)

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规格:
  • 50T
  • 100T
数量:
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概述
货号HY363117
品牌abinScience
种属反应性Human, Mouse, Rat, Bovine
应用ELISA, FCM, IF(P), WB
宿主Mouse
同种型IgG2a
克隆号5D2
偶联物FITC
克隆类型Monoclonal
靶标Phospholipase A1, LIPD, Lipoprotein lipase, LPL
内毒素水平Please contact with the lab for this information.
相关产品 Mouse IgG2a Recombinant Isotype Control Antibody (C1.18.4), FITC
Accession号P06858
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Store at 4°C for 12 months. Protect from light. Do not freeze.
背景

Lipoprotein lipase (LPL/LIPD) is a ~53 kDa protein. Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Although it has both phospholipase and triglyceride lipase activities it is primarily a triglyceride lipase with low but detectable phospholipase activity. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.

1. Lutz, EP. et al. (2001) The Journal of clinical investigation 107, 1183-92. PMID: 11342582
2. Pingitore, P. et al. (2016) Journal of clinical lipidology 10, 816-823. PMID: 27578112
3. Weinstock, PH. et al. (1995) The Journal of clinical investigation 96, 2555-68. PMID: 8675619
4. McCoy, MG. et al. (2002) Journal of lipid research 43, 921-9. PMID: 12032167
5. Dugi, KA. et al. (1995) The Journal of biological chemistry 270, 25396-401. PMID: 7592706
6. Goulbourne, CN. et al. (2014) Cell metabolism 19, 849-60. PMID: 24726386
7. Allan, CM. et al. (2017) Journal of lipid research 58, 216-225. PMID: 27811232
NoteFor flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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