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Anti-Human CD55/DAF Recombinant Antibody (SAA0839), FITC (HY307217)

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规格:
  • 50T
  • 100T
数量:
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概述
货号HY307217
品牌abinScience
种属反应性Human
应用ELISA, FCM, WB
宿主Mouse
同种型IgG2a
克隆号SAA0839
偶联物FITC
克隆类型Monoclonal
靶标Complement decay-accelerating factor, CR, DAF, CD55
内毒素水平Please contact with the lab for this information.
相关产品 Mouse IgG2a Recombinant Isotype Control Antibody (C1.18.4), FITC
Accession号P08174
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Store at 4°C for 12 months. Protect from light. Do not freeze.
背景

Complement decay-accelerating factor (CD55) is a ~41 kDa protein. This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage.

1. Ward, T. et al. (1994) The EMBO journal 13, 5070-4. PMID: 7525274
2. Ozen, A. et al. (2017) The New England journal of medicine 377, 52-61. PMID: 28657829
NoteFor flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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