

| 货号 | HB873117 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Human |
| 应用 | FCM |
| 宿主 | Human |
| 同种型 | IgG1, kappa |
| 克隆号 | SAA0040 |
| 偶联物 | FITC |
| 克隆类型 | Monoclonal |
| 靶标 | APT1, TNFRSF6, FAS1, FASLG receptor, CD95, Apo-1 antigen, Tumor necrosis factor receptor superfamily member 6, FAS, Apoptosis-mediating surface antigen FAS |
| 内毒素水平 | Please contact with the lab for this information. |
| 相关产品 | Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), FITC |
| Accession号 | P25445 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 背景 | Tumor necrosis factor receptor superfamily member 6 (CD95/FAS) is a ~37 kDa protein. Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase CASP8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs CASP8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |

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