

| 货号 | HW651117 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Human |
| 应用 | FCM, WB |
| 宿主 | Human |
| 同种型 | IgG2, kappa |
| 克隆号 | SAA0129 |
| 偶联物 | FITC |
| 克隆类型 | Monoclonal |
| 靶标 | Serine/threonine-protein kinase receptor R3, ACVRL1, Activin receptor-like kinase 1, ALK-1, ACVRLK1, ALK1, SKR3, TGF-B superfamily receptor type I, TSR-I |
| 内毒素水平 | Please contact with the lab for this information. |
| 相关产品 | Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10), FITC |
| Accession号 | P37023 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 背景 | Activin receptor type-1-like (ACVRL1/ALK-1) is a ~56 kDa protein. Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well. |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |

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