

| 货号 | ARO-A10537 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human CD45RO Antibody (UCHL1), PE [UCHL1] (ARO-A10537) is a rabbit monoclonal antibody detecting T200, Leukocyte common antigen, CD45, L-CA, Receptor-type tyrosine-protein phosphatase C, PTPRC in FCM. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | FCM |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 克隆号 | UCHL1 |
| 偶联物 | PE |
| 克隆类型 | Monoclonal |
| 靶标 | T200, Leukocyte common antigen, CD45, L-CA, Receptor-type tyrosine-protein phosphatase C, PTPRC |
| 内毒素水平 | Please contact with the lab for this information. |
| Accession号 | P08575 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 背景 | Receptor-type tyrosine-protein phosphatase C (CD45RO) is a ~147 kDa protein. Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. 1. Dunlock, VE. et al. (2022) Cell reports 39, 111006. PMID: 35767951 |
| Note | For research use only. |

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