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Anti-Human IL1B/IL1F2 Antibody (SAA0368), APC (ARO-A10423)

概述
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参考文献

概述

货号	ARO-A10423
品牌	ProteoGenix
描述	Anti-Human IL1B/IL1F2 Antibody (SAA0368), APC [SAA0368] (ARO-A10423) is a mouse monoclonal antibody detecting Interleukin-1 beta, IL1B, Catabolin, IL1F2, IL-1 beta, IL-1β in ELISA, FCM. Suitable for Human. Highlights Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, FCM
宿主	Mouse
同种型	IgG2a, kappa
克隆号	SAA0368
偶联物	APC
克隆类型	Monoclonal
靶标	Interleukin-1 beta, IL1B, Catabolin, IL1F2, IL-1 beta, IL-1β
内毒素水平	Please contact with the lab for this information.
Accession号	P01584
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Interleukin-1 beta (IL1B/IL1F2) is a ~30 kDa protein. Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. IL1B is the therapeutic target of canakinumab (Ilaris). 1. Tominaga, K. et al. (2000) International immunology 12, 151-60. PMID: 10653850 2. Nakahara, H. et al. (2003) Arthritis and rheumatism 48, 1521-9. PMID: 12794819 3. LaRock, CN. et al. (2016) Science immunology 1. PMID: 28331908 4. Van Damme, J. et al. (1985) Nature 314, 266-8. PMID: 3920526 5. Tian, XX. et al. (2021) International endodontic journal 54, 916-925. PMID: 33377178 6. Xia, S. et al. (2021) Nature 593, 607-611. PMID: 33883744
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

×

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

=

工作液

C₂ (终浓度)

×

V₂ (终体积)

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Anti-Human IL1B/IL1F2 Antibody (SAA0368), APC

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