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Anti-Human CD55 Antibody (TS55), FITC (ARO-A10801)

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概述
货号ARO-A10801
品牌ProteoGenix
描述
Anti-Human CD55 Antibody (TS55), FITC [TS55] (ARO-A10801) is a mouse monoclonal antibody detecting Complement decay-accelerating factor, CR, DAF, CD55 in FCM. Suitable for Human.
Highlights
  • Validated for FCM — Optimized for consistent performance.
种属反应性Human
应用FCM
宿主Mouse
同种型IgG1, kappa
克隆号TS55
偶联物FITC
克隆类型Monoclonal
靶标Complement decay-accelerating factor, CR, DAF, CD55
内毒素水平Please contact with the lab for this information.
Accession号P08174
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Store at 4°C for 12 months. Protect from light. Do not freeze.
背景

Complement decay-accelerating factor (CD55) is a ~41 kDa protein. This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage.

1. Ward, T. et al. (1994) The EMBO journal 13, 5070-4. PMID: 7525274
2. Ozen, A. et al. (2017) The New England journal of medicine 377, 52-61. PMID: 28657829
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Human CD55 Antibody (TS55), FITC

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