

| 货号 | ARO-A10966 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Mouse CD282/TLR2 Antibody (SAA1384), FITC [SAA1384] (ARO-A10966) is a mouse monoclonal antibody detecting TIL4, Toll-like receptor 2, TLR2, Toll/interleukin-1 receptor-like protein 4, CD282 in FCM, IF, WB. Suitable for Mouse.
Highlights
|
| 种属反应性 | Mouse |
| 应用 | FCM, IF, WB |
| 宿主 | Mouse |
| 同种型 | IgG2a, kappa |
| 克隆号 | SAA1384 |
| 偶联物 | FITC |
| 克隆类型 | Monoclonal |
| 靶标 | TIL4, Toll-like receptor 2, TLR2, Toll/interleukin-1 receptor-like protein 4, CD282 |
| 内毒素水平 | Please contact with the lab for this information. |
| Accession号 | Q9QUN7 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 背景 | Toll-like receptor 2 (CD282/TLR2) is a ~89 kDa protein. Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. 1. Hoebe, K. et al. (2005) Nature 433, 523-7. PMID: 15690042 2. Pathak, SK. et al. (2007) Nature immunology 8, 610-8. PMID: 17486091 3. Drage, MG. et al. (2009) Cellular immunology 258, 29-37. PMID: 19362712 4. Chen, ST. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 188, 668-77. PMID: 22174456 5. Deboosère, N. et al. (2017) Cellular microbiology 19. PMID: 27220037 |
| Note | For research use only. |

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