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Anti-Human CD358/TNFRSF21 Antibody (M53-E04), FITC (ARO-A10961)

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概述
货号ARO-A10961
品牌ProteoGenix
描述
Anti-Human CD358/TNFRSF21 Antibody (M53-E04), FITC [M53-E04] (ARO-A10961) is a mouse monoclonal antibody detecting DR6, Death receptor 6, Tumor necrosis factor receptor superfamily member 21, TNFRSF21, CD358 in FCM. Suitable for Human.
Highlights
  • Validated for FCM — Optimized for consistent performance.
种属反应性Human
应用FCM
宿主Mouse
同种型IgG1, kappa
克隆号M53-E04
偶联物FITC
克隆类型Monoclonal
靶标DR6, Death receptor 6, Tumor necrosis factor receptor superfamily member 21, TNFRSF21, CD358
内毒素水平Please contact with the lab for this information.
Accession号O75509
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Store at 4°C for 12 months. Protect from light. Do not freeze.
背景

Tumor necrosis factor receptor superfamily member 21 (CD358/TNFRSF21) is a ~71 kDa protein. Promotes apoptosis, possibly via a pathway that involves the activation of NF-kappa-B. Can also promote apoptosis mediated by BAX and by the release of cytochrome c from the mitochondria into the cytoplasm. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). Negatively regulates oligodendrocyte survival, maturation and myelination. Plays a role in signaling cascades triggered by stimulation of T-cell receptors, in the adaptive immune response and in the regulation of T-cell differentiation and proliferation.

1. Zhang, JY. et al. (2021) Cell research 31, 980-997. PMID: 34012073
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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