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Anti-Human CD218a/IL18R1 Recombinant Antibody (1G12), FITC (HC691117)

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规格:
  • 50T
  • 100T
数量:
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概述
货号HC691117
品牌abinScience
种属反应性Human
应用FCM
宿主Mouse
同种型IgG1, kappa
克隆号1G12
偶联物FITC
克隆类型Monoclonal
靶标CD218a, IL-18R1, IL18R1, CDw218a, IL-18R-alpha, IL-18R-1, Interleukin-18 receptor 1, IL-18Ralpha, IL1 receptor-related protein, CD218 antigen-like family member A, IL-1Rrp, IL1RRP, IL1R-rp, Interleukin-18 receptor alpha
内毒素水平Please contact with the lab for this information.
相关产品 Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), FITC
Accession号Q13478
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Store at 4°C for 12 months. Protect from light. Do not freeze.
背景

Interleukin-18 receptor 1 (CD218a/IL18R1) is a ~62 kDa protein. Within the IL18 receptor complex, responsible for the binding of the pro-inflammatory cytokine IL18, but not IL1A nor IL1B. Involved in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells. Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3.

1. Kato, Z. et al. (2003) Nature structural biology 10, 966-71. PMID: 14528293
2. Wei, H. et al. (2014) FEBS letters 588, 3838-43. PMID: 25261253
3. Tsutsumi, N. et al. (2014) Nature communications 5, 5340. PMID: 25500532
4. Shi, X. et al. (2023) Nature 624, 442-450. PMID: 37993714
5. Parnet, P. et al. (1996) The Journal of biological chemistry 271, 3967-70. PMID: 8626725
6. Tominaga, K. et al. (2000) International immunology 12, 151-60. PMID: 10653850
NoteFor flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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