Anti-Human Integrin alpha V/CD51 Recombinant Antibody (17E6#), APC (HY065137)

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50T
100T

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货号	HY065137
品牌	abinScience
种属反应性	Human
应用	ELISA, FCM, WB
宿主	Mouse
同种型	IgG1, kappa
克隆号	17E6#
偶联物	APC
克隆类型	Monoclonal
经测试应用	FCM
靶标	MSK8, VNRA, Vitronectin receptor, Integrin alpha-V, Vitronectin receptor subunit alpha, CD51, ITGAV, VTNR
内毒素水平	Please contact with the lab for this information.
相关产品	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC
Accession号	P06756
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Integrin alpha-V (CD51/ITGAV) is a ~116 kDa protein. The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. ITGAV:ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling. ITGAV:ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV:ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. 1. Fujita, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 5809-19. PMID: 23125415 2. Ieguchi, K. et al. (2010) The Journal of biological chemistry 285, 31388-98. PMID: 20682778 3. Mori, S. et al. (2008) The Journal of biological chemistry 283, 18066-75. PMID: 18441324 4. Mori, S. et al. (2017) Bioscience reports 37. PMID: 28302677 5. Saegusa, J. et al. (2009) The Journal of biological chemistry 284, 24106-14. PMID: 19578119 6. Cedano Prieto, DM. et al. (2017) PloS one 12, e0184285. PMID: 28873464 7. Takada, YK. et al. (2017) The Journal of biological chemistry 292, 20067-20075. PMID: 29030430 8. Saegusa, J. et al. (2008) The Journal of biological chemistry 283, 26107-15. PMID: 18635536 9. Fujita, M. et al. (2015) The Journal of biological chemistry 290, 259-71. PMID: 25398877 10. Bax, DV. et al. (2003) The Journal of biological chemistry 278, 34605-16. PMID: 12807887
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

Flow CytoMetry

Flow-cytometry using APC anti-human CD51 antibody. HepG-2 cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CD51 monoclonal antibody (Catalog: HY065137, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

产品说明书

Anti-Human Integrin alpha V/CD51 Recombinant Antibody (17E6#), APC.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

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Anti-Human Integrin alpha V/CD51 Recombinant Antibody (17E6#), APC (HY065137)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

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实验相关试剂

Anti-Human Integrin alpha V/CD51 Recombinant Antibody (17E6#), APC (HY065137)

概述

图片

参考文献

产品说明书

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