

| 货号 | ICH3056CB | ||||
|---|---|---|---|---|---|
| 品牌 | IchorBio | ||||
| 描述 |
Indirect Human B Cell Depletion Kit (ICH3056CB) is a antibody targeting CD19 (B cell). Reactive with Human. Validated for Cell isolation / separation (flow cytometry, cell culture, functional & cell-therapy research).
Highlights
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| 种属反应性 | Human | ||||
| 应用 | Cell isolation / separation (flow cytometry, cell culture, functional & cell-therapy research) | ||||
| 克隆类型 | Monoclonal | ||||
| 经测试应用 | Cell isolation / separation (flow cytometry, cell culture, functional & cell-therapy research) | ||||
| 靶标 | CD19 (B cell) | ||||
| 特异性 | CD19 (B cell) | ||||
| Accession号 | P15391 | ||||
| 状态 | Liquid | ||||
| 运输 | Blue Ice | ||||
| 产品使用信息 |
| ||||
| 稳定性和存储 | Store at 2–8°C; do not freeze | ||||
| 规格 | Size: 100T | ||||
| 背景 | B cells (CD19+) are the primary mediators of humoral immunity, responsible for antibody production, antigen presentation, and immune memory, and their selective depletion enables the enrichment of untouched non-B cell populations for studies where B cell contamination would confound downstream analysis. Removing this population without disturbing the target cells' physiological state is essential for applications such as T cell or NK cell functional assays and immune profiling. The Ichorbio Indirect Human CD19+ B Cell Depletion Kit depletes CD19+ B cells from PBMCs via a column-based indirect magnetic labeling strategy, in which biotin-conjugated CD19 antibodies are bound by anti-biotin magnetic nanobeads and retained in the separation column, allowing untouched non-B cell populations to be recovered in the flow-through, achieving depletion efficiency up to 99.1% (residual B cell proportion of 0.091%), yielding high-purity, untouched target cell populations suitable for downstream functional and immunological studies. CD19 is expressed on B lymphocytes from the pro-B stage through plasmablasts (downregulated on mature plasma cells); a pan-B-cell marker. | ||||
| Note | Research Use Only (RUO) |

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