Anti-Human MCAM/CD146 Recombinant Antibody (C3.19.1), APC (HW484137)

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货号	HW484137
品牌	abinScience
种属反应性	Human
应用	FCM
宿主	Mouse
同种型	IgG2a, kappa
克隆号	C3.19.1
偶联物	APC
克隆类型	Monoclonal
经测试应用	FCM
靶标	CD146, Melanoma cell adhesion molecule, S-endo 1 endothelial-associated antigen, Melanoma-associated antigen A32, MUC18, MCAM, Melanoma-associated antigen MUC18, Cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12
内毒素水平	Please contact with the lab for this information.
相关产品	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), APC
Accession号	P43121
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Cell surface glycoprotein MUC18 (CD146/MCAM) is a ~71 kDa protein. Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as a surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

Flow CytoMetry

Flow-cytometry using APC anti-human CD146 antibody. Hela cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CD146 monoclonal antibody (Catalog: HW484137, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

产品说明书

Anti-Human MCAM/CD146 Recombinant Antibody (C3.19.1), APC.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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Anti-Human MCAM/CD146 Recombinant Antibody (C3.19.1), APC (HW484137)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human MCAM/CD146 Recombinant Antibody (C3.19.1), APC (HW484137)

概述

图片

参考文献

产品说明书

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