Anti-Human CD178/FASLG/TNFSF6 Recombinant Antibody (NOK2/NOK-2), APC (HW497137)

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货号	HW497137
品牌	abinScience
种属反应性	Human
应用	FCM
宿主	Mouse
同种型	IgG2a, kappa
克隆号	NOK2/NOK-2
偶联物	APC
克隆类型	Monoclonal
靶标	Receptor-binding FasL ectodomain, APL, APT1LG1, FasL ICD, Fas antigen ligand, CD178, sFasL, CD95L, APTL, TNFSF6, Apoptosis antigen ligand, SPA, FASLG, FasL, SPPL2A-processed FasL form, Tumor necrosis factor ligand superfamily member 6, Soluble Fas ligand, Fas ligand, CD95 ligand, CD95-L, FASL
内毒素水平	Please contact with the lab for this information.
相关产品	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), APC
Accession号	P48023
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Tumor necrosis factor ligand superfamily member 6 (CD178/FASLG) is a ~31 kDa protein. Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis also has a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis. 1. Ruiz-García, R. et al. (2015) Pediatric research 78, 603-8. PMID: 26334989 2. Schneider, P. et al. (1997) The Journal of biological chemistry 272, 18827-33. PMID: 9228058 3. Alderson, MR. et al. (1995) The Journal of experimental medicine 181, 71-7. PMID: 7528780 4. Tanaka, M. et al. (1998) Nature medicine 4, 31-6. PMID: 9427603 5. Liu, W. et al. (2016) Structure (London, England : 1993) 24, 2016-2023. PMID: 27806260
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

产品说明书

Anti-Human CD178/FASLG/TNFSF6 Recombinant Antibody (NOK2/NOK-2), APC.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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C₁ × V₁ = C₂ × V₂

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C₁ (起始浓度)

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Anti-Human CD178/FASLG/TNFSF6 Recombinant Antibody (NOK2/NOK-2), APC (HW497137)

概述

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参考文献

产品说明书

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重组蛋白

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实验相关试剂

Anti-Human CD178/FASLG/TNFSF6 Recombinant Antibody (NOK2/NOK-2), APC (HW497137)

概述

图片

参考文献

产品说明书

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