

| 货号 | HW762137 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Human |
| 应用 | ELISA, FCM |
| 宿主 | Mouse |
| 同种型 | IgG2a, kappa |
| 克隆号 | SAA0458 |
| 偶联物 | APC |
| 克隆类型 | Monoclonal |
| 靶标 | Small-inducible cytokine A11, SCYA11, Eotaxin, CCL11, Eosinophil chemotactic protein, C-C motif chemokine 11, Eotaxin1, Eotaxin-1 |
| 内毒素水平 | Please contact with the lab for this information. |
| 相关产品 | Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), APC |
| Accession号 | P51671 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 背景 | Eotaxin (CCL11) is a ~10 kDa protein. Chemokine that plays a central role in both allergic and non-allergic inflammatory reactions by inducing the migration of different leukocyte types including eosinophils, basophils, macrophages and dendritic cells. Exerts its effects primarily by binding to the CCR3 receptor. Induces also chemotaxis of endothelial cells and promotes angiogenesis by activating the PI3K/Akt pathway. 1. Garcia-Zepeda, EA. et al. (1996) Nature medicine 2, 449-56. PMID: 8597956 2. Wakabayashi, K. et al. (2021) Scientific reports 11, 7937. PMID: 33846499 3. Kitaura, M. et al. (1996) The Journal of biological chemistry 271, 7725-30. PMID: 8631813 4. Park, JY. et al. (2017) Journal of receptor and signal transduction research 37, 416-421. PMID: 28279120 |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |

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