Anti-Human CD196/CCR6 Recombinant Antibody (R612), APC (HW383137)

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货号	HW383137
品牌	abinScience
种属反应性	Human
应用	FCM
宿主	Mouse
同种型	IgG1, kappa
克隆号	R612
偶联物	APC
克隆类型	Monoclonal
靶标	GPRCY4, C-C chemokine receptor type 6, CCR-6, LARC receptor, CD196, CKRL3, G-protein coupled receptor 29, CKR-L3, DRY6, STRL22, GPR-CY4, GPR29, CCR6, Chemokine receptor-like 3, CMKBR6, C-C CKR-6, CC-CKR-6
内毒素水平	Please contact with the lab for this information.
相关产品	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC
Accession号	P51684
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	C-C chemokine receptor type 6 (CD196/CCR6) is a ~42 kDa protein. Receptor for the C-C type chemokine CCL20. Binds to CCL20 and subsequently transduces a signal by increasing the intracellular calcium ion levels. Although CCL20 is its major ligand it can also act as a receptor for non-chemokine ligands such as beta-defensins. Binds to defensin DEFB1 leading to increase in intracellular calcium ions and cAMP levels. Its binding to DEFB1 is essential for the function of DEFB1 in regulating sperm motility and bactericidal activity. 1. Baba, M. et al. (1997) The Journal of biological chemistry 272, 14893-8. PMID: 9169459 2. Röhrl, J. et al. (2010) The Journal of biological chemistry 285, 7028-34. PMID: 20068036 3. Lee, AY. et al. (2015) Cytokine 72, 97-101. PMID: 25585877 4. Diao, R. et al. (2014) Science translational medicine 6, 249ra108. PMID: 25122636 5. Ito, T. et al. (2011) Experimental cell research 317, 613-9. PMID: 21376174 6. Caballero-Campo, P. et al. (2014) Journal of cellular physiology 229, 68-78. PMID: 23765988
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

产品说明书

Anti-Human CD196/CCR6 Recombinant Antibody (R612), APC.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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C₁ × V₁ = C₂ × V₂

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C₁ (起始浓度)

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Anti-Human CD196/CCR6 Recombinant Antibody (R612), APC (HW383137)

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重组蛋白

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实验相关试剂

Anti-Human CD196/CCR6 Recombinant Antibody (R612), APC (HW383137)

概述

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参考文献

产品说明书

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