

| 货号 | ICH8018 |
|---|---|
| 品牌 | IchorBio |
| 描述 |
Pacmilimab PK ELISA Kit (ICH8018) is a antibody targeting PD-L1. Validated for PK ELISA.
Highlights
|
| 应用 | PK ELISA |
| 克隆类型 | Monoclonal |
| 经测试应用 | PK ELISA |
| 靶标 | PD-L1 |
| Accession号 | Q9NZQ7 |
| 状态 | Liquid |
| 保存溶液 | Pre-coated 96-well plate, standards, detection antibody, streptavidin-HRP, buffers Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 运输 | Blue Ice |
| 稳定性和存储 | The ELISA Kit should be stored at 2–8°C and is stable for up to 6 months when unopened, unless otherwise stated on the product label or datasheet. Components stored separately may remain stable for up to 12 months under recommended conditions. After opening, keep components tightly capped at 2–8°C. Prepared working solutions should be used on the day of preparation, and repeated freeze-thaw cycles of protein-containing reagents, including reconstituted standards/calibrators, should be avoided. |
| 规格 | Size: 96T |
| 别名 | CX-072, 2145091-51-4 |
| 背景 | Pacmilimab is a Probody therapeutic targeting PD-L1, engineered as a conditionally activated monoclonal antibody that remains masked in circulation and becomes activated within the tumor microenvironment through tumor-associated protease cleavage. This design aims to localize immune checkpoint blockade activity to tumors while reducing systemic immune-related toxicity. Once activated, pacmilimab blocks PD-L1 interaction with PD-1, restoring T-cell–mediated antitumor responses. The antibody has been evaluated in early clinical studies as a strategy to improve the therapeutic index of PD-L1 inhibition. |
| Note | For research only |

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