Anti-Human ErbB2/Her2 Recombinant Antibody (4D5V8), PerCP (HY286147)

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货号	HY286147
品牌	abinScience
种属反应性	Human
应用	FCM
宿主	Human
同种型	IgG1, kappa
克隆号	4D5V8
偶联物	PerCP
克隆类型	Monoclonal
靶标	p185erbB2, HER2, NGL, Tyrosine kinase-type cell surface receptor HER2, NEU, MLN 19, Proto-oncogene Neu, MLN19, ERBB2, Proto-oncogene c-ErbB-2, CD340, Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein
内毒素水平	Please contact with the lab for this information.
相关产品	Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), PerCP
Accession号	P04626
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Receptor tyrosine-protein kinase erbB-2 (CD340/ERBB2) is a ~137 kDa protein. Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. CD340 is the therapeutic target of trastuzumab (Herceptin) and trastuzumab deruxtecan (Enhertu).
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

产品说明书

Anti-Human ErbB2/Her2 Recombinant Antibody (4D5V8), PerCP.pdf

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Anti-Human ErbB2/Her2 Recombinant Antibody (4D5V8), PerCP (HY286147)

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参考文献

产品说明书

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Anti-Human ErbB2/Her2 Recombinant Antibody (4D5V8), PerCP (HY286147)

概述

图片

参考文献

产品说明书

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