

| 货号 | HY350147 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Human |
| 应用 | ELISA, FCM |
| 宿主 | Mouse |
| 同种型 | IgG2a |
| 克隆号 | T-2 |
| 偶联物 | PerCP |
| 克隆类型 | Monoclonal |
| 靶标 | Low affinity neurotrophin receptor p75NTR, TNFRSF16, CD271, Gp80-LNGFR, p75 ICD, Low-affinity nerve growth factor receptor, NGFR, NGF receptor, Tumor necrosis factor receptor superfamily member 16 |
| 内毒素水平 | Please contact with the lab for this information. |
| 相关产品 | Mouse IgG2a Recombinant Isotype Control Antibody (C1.18.4), PerCP |
| Accession号 | P08138 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 背景 | Tumor necrosis factor receptor superfamily member 16 (CD271/NGFR) is a ~45 kDa protein. Low affinity receptor which can bind to NGF, BDNF, NTF3, and NTF4. Forms a heterodimeric receptor with SORCS2 that binds the precursor forms of NGF, BDNF and NTF3 with high affinity, and has much lower affinity for mature NGF and BDNF. Plays an important role in differentiation and survival of specific neuronal populations during development. Can mediate cell survival as well as cell death of neural cells. Plays a role in the inactivation of RHOA. 1. Glerup, S. et al. (2014) Neuron 82, 1074-87. PMID: 24908487 2. Lin, Z. et al. (2015) eLife 4, e11692. PMID: 26646181 3. Baeza-Raja, B. et al. (2013) The Journal of neuroscience : the official journal of the Society for Neuroscience 33, 10221-34. PMID: 23785138 4. Li, H. et al. (2012) Science China. Life sciences 55, 367-74. PMID: 22566094 |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |

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