Anti-Mouse CD19 Recombinant Antibody (1D3), PerCP (MB996147)

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货号	MB996147
品牌	abinScience
种属反应性	Mouse
应用	FCM
宿主	Rat
同种型	IgG2a, kappa
克隆号	1D3
偶联物	PerCP
克隆类型	Monoclonal
靶标	B-lymphocyte antigen CD19, Differentiation antigen CD19, CD19
内毒素水平	Please contact with the lab for this information.
相关产品	Rat IgG2a, kappa Recombinant Isotype Control Antibody (RTK2758), PerCP
Accession号	P25918
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	B-lymphocyte antigen CD19 is a ~60 kDa protein. Functions as a coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. CD19 is the therapeutic target of tafasitamab (Monjuvi). 1. Wang, Y. et al. (2002) Immunity 17, 501-14. PMID: 12387743 2. Ishiura, N. et al. (2010) European journal of immunology 40, 1192-204. PMID: 20101619 3. Buhl, AM. et al. (1997) The Journal of experimental medicine 186, 1897-910. PMID: 9382888 4. Engel, P. et al. (1995) Immunity 3, 39-50. PMID: 7542548 5. Rickert, RC. et al. (1995) Nature 376, 352-5. PMID: 7543183 6. Sato, S. et al. (1997) Journal of immunology (Baltimore, Md. : 1950) 159, 3278-87. PMID: 9317126
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

产品说明书

Anti-Mouse CD19 Recombinant Antibody (1D3), PerCP.pdf

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Anti-Mouse CD19 Recombinant Antibody (1D3), PerCP (MB996147)

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Anti-Mouse CD19 Recombinant Antibody (1D3), PerCP (MB996147)

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