Anti-Mouse NKG2D/CD314 Recombinant Antibody (CX5), PerCP (MB123247)

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货号	MB123247
品牌	abinScience
种属反应性	Mouse
应用	ELISA, FCM
宿主	Rat
同种型	IgG1, kappa
克隆号	CX5
偶联物	PerCP
克隆类型	Monoclonal
靶标	NKG2-D type II integral membrane protein, Killer cell lectin-like receptor subfamily K member 1, NK cell receptor D, NKG2-D-activating NK receptor, CD314, Klrk1, Nkg2d
内毒素水平	Please contact with the lab for this information.
相关产品	Rat IgG1, kappa Recombinant Isotype Control Antibody (ES26-14D1.11), PerCP
Accession号	O54709
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	NKG2-D type II integral membrane protein (CD314/KLRK1) is a ~26 kDa protein. Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF.
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

产品说明书

Anti-Mouse NKG2D/CD314 Recombinant Antibody (CX5), PerCP.pdf

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Anti-Mouse NKG2D/CD314 Recombinant Antibody (CX5), PerCP (MB123247)

概述

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参考文献

产品说明书

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实验相关试剂

Anti-Mouse NKG2D/CD314 Recombinant Antibody (CX5), PerCP (MB123247)

概述

图片

参考文献

产品说明书

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