

| 货号 | HB199147 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Human |
| 应用 | FCM |
| 宿主 | Human |
| 同种型 | IgG1, kappa |
| 克隆号 | SAA0549 |
| 偶联物 | PerCP |
| 克隆类型 | Monoclonal |
| 靶标 | sCD40L, Tumor necrosis factor ligand superfamily member 5, T-cell antigen Gp39, CD40L, TNFSF5, CD154, CD40-L, TNF-related activation protein, CD40 ligand, CD40LG, TRAP |
| 内毒素水平 | Please contact with the lab for this information. |
| 相关产品 | Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), PerCP |
| Accession号 | P29965 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 背景 | CD40 ligand (CD154/CD40L) is a ~29 kDa protein. Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation. Induces the activation of NF-kappa-B. Induces the activation of kinases MAPK8 and PAK2 in T-cells. 1. Graf, D. et al. (1992) European journal of immunology 22, 3191-4. PMID: 1280226 2. Takada, YK. et al. (2019) Journal of immunology (Baltimore, Md. : 1950) 203, 1383-1391. PMID: 31331973 3. Blotta, MH. et al. (1996) Journal of immunology (Baltimore, Md. : 1950) 156, 3133-40. PMID: 8617933 4. Mikolajczak, SA. et al. (2004) The Journal of experimental medicine 199, 1025-31. PMID: 15067037 |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |

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