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Anti-Human CD178/FASLG/TNFSF6 Recombinant Antibody (NOK1/NOK-1), PerCP (HW497247)

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规格:
  • 50T
  • 100T
数量:
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概述
货号HW497247
品牌abinScience
种属反应性Human
应用FCM
宿主Mouse
同种型IgG2a, kappa
克隆号NOK1/NOK-1
偶联物PerCP
克隆类型Monoclonal
靶标Receptor-binding FasL ectodomain, APL, APT1LG1, FasL ICD, Fas antigen ligand, CD178, sFasL, CD95L, APTL, TNFSF6, Apoptosis antigen ligand, SPA, FASLG, FasL, SPPL2A-processed FasL form, Tumor necrosis factor ligand superfamily member 6, Soluble Fas ligand, Fas ligand, CD95 ligand, CD95-L, FASL
内毒素水平Please contact with the lab for this information.
相关产品 Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), PerCP
Accession号P48023
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Store at 4°C for 12 months. Protect from light. Do not freeze.
背景

Tumor necrosis factor ligand superfamily member 6 (CD178/FASLG) is a ~31 kDa protein. Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis also has a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis.

1. Ruiz-García, R. et al. (2015) Pediatric research 78, 603-8. PMID: 26334989
2. Schneider, P. et al. (1997) The Journal of biological chemistry 272, 18827-33. PMID: 9228058
3. Alderson, MR. et al. (1995) The Journal of experimental medicine 181, 71-7. PMID: 7528780
4. Tanaka, M. et al. (1998) Nature medicine 4, 31-6. PMID: 9427603
5. Liu, W. et al. (2016) Structure (London, England : 1993) 24, 2016-2023. PMID: 27806260
NoteFor flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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