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Anti-Human CX3CL1/Fractalkine Recombinant Antibody (SAA0469), PerCP (HX143147)

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规格:
  • 50T
  • 100T
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概述
货号HX143147
品牌abinScience
种属反应性Human
应用ELISA, FCM
宿主Mouse
同种型IgG2a, kappa
克隆号SAA0469
偶联物PerCP
克隆类型Monoclonal
靶标Small-inducible cytokine D1, Fractalkine, Neurotactin, C-X3-C motif chemokine 1, NTT, CX3CL1, SCYD1, FKN, CX3C membrane-anchored chemokine
内毒素水平Please contact with the lab for this information.
相关产品 Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), PerCP
Accession号P78423
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Store at 4°C for 12 months. Protect from light. Do not freeze.
背景

Fractalkine (CX3CL1) is a ~42 kDa protein. Chemokine that acts as a ligand for both CX3CR1 and integrins ITGAV:ITGB3 and ITGA4:ITGB1. The CX3CR1-CX3CL1 signaling exerts distinct functions in different tissue compartments, such as immune response, inflammation, cell adhesion and chemotaxis. Regulates leukocyte adhesion and migration processes at the endothelium. Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner. In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site (site 1) in integrins.

1. Nishimura, M. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 168, 6173-80. PMID: 12055230
2. Xue, X. et al. (2011) PLoS pathogens 7, e1002162. PMID: 21829356
3. Fujita, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 5809-19. PMID: 23125415
4. Fong, AM. et al. (1998) The Journal of experimental medicine 188, 1413-9. PMID: 9782118
5. Mizoue, LS. et al. (1999) Biochemistry 38, 1402-14. PMID: 9931005
6. Bazan, JF. et al. (1997) Nature 385, 640-4. PMID: 9024663
7. Pan, Y. et al. (1997) Nature 387, 611-7. PMID: 9177350
8. Fujita, M. et al. (2014) PloS one 9, e96372. PMID: 24789099
NoteFor flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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