

| 货号 | MV563147 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Mouse |
| 应用 | FCM |
| 宿主 | Mouse |
| 同种型 | IgG1, kappa |
| 克隆号 | SAA0332 |
| 偶联物 | PerCP |
| 克隆类型 | Monoclonal |
| 靶标 | A8, Semaphorin-4D, GR3, BB18, SEMAJ, C9orf164, CD100, SEMA4D |
| 内毒素水平 | Please contact with the lab for this information. |
| 相关产品 | Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), PerCP |
| Accession号 | O09126 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 背景 | Semaphorin-4D (CD100/SEMA4D) is a ~95 kDa protein. Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling. Regulates GABAergic synapse development. Promotes the development of inhibitory synapses in a PLXNB1-dependent manner. Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA. Promotes the migration of cerebellar granule cells. 1. Kuzirian, MS. et al. (2013) The Journal of neuroscience : the official journal of the Society for Neuroscience 33, 8961-73. PMID: 23699507 2. McDermott, JE. et al. (2018) Molecular and cellular neurosciences 92, 50-66. PMID: 29981480 3. Deng, S. et al. (2007) The Journal of neuroscience : the official journal of the Society for Neuroscience 27, 6333-47. PMID: 17554007 |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |

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