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Anti-Human CD84/SLAMF5 Recombinant Antibody (SAA0037), PerCP (HV297147)

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  • 50T
  • 100T
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概述
货号HV297147
品牌abinScience
种属反应性Human
应用FCM
宿主Mouse
同种型IgG2a
克隆号SAA0037
偶联物PerCP
克隆类型Monoclonal
靶标Signaling lymphocytic activation molecule 5, Hly9-beta, Cell surface antigen MAX.3, Leukocyte differentiation antigen CD84, CD84, SLAM family member 5, SLAMF5
内毒素水平Please contact with the lab for this information.
相关产品 Mouse IgG2a Recombinant Isotype Control Antibody (C1.18.4), PerCP
Accession号Q9UIB8
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Store at 4°C for 12 months. Protect from light. Do not freeze.
背景

SLAM family member 5 (CD84) is a ~38 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Can mediate natural killer (NK) cell cytotoxicity dependent on SH2D1A and SH2D1B. Increases proliferative responses of activated T-cells and SH2D1A/SAP does not seem be required for this process.

1. Martin, M. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 3668-76. PMID: 11564780
2. Tangye, SG. et al. (2002) European journal of immunology 32, 1640-9. PMID: 12115647
3. Tangye, SG. et al. (2003) Journal of immunology (Baltimore, Md. : 1950) 171, 2485-95. PMID: 12928397
4. Zaiss, M. et al. (2003) Experimental hematology 31, 798-805. PMID: 12962726
5. Nanda, N. et al. (2005) Blood 106, 3028-34. PMID: 16037392
6. Álvarez-Errico, D. et al. (2011) Journal of immunology (Baltimore, Md. : 1950) 187, 5577-86. PMID: 22068234
7. Agod, Z. et al. (2018) Frontiers in immunology 9, 62. PMID: 29434592
NoteFor flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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