

| 货号 | HT061127 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Human |
| 应用 | FCM |
| 宿主 | Mouse |
| 同种型 | IgG1, kappa |
| 克隆号 | BGA1831 |
| 偶联物 | PE |
| 克隆类型 | Monoclonal |
| 靶标 | NKp30, LY117, NCR3, 1C7, NK-p30, CD337, Natural cytotoxicity triggering receptor 3, Activating natural killer receptor p30, Natural killer cell p30-related protein |
| 内毒素水平 | Please contact with the lab for this information. |
| 相关产品 | Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), PE |
| Accession号 | O14931 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 背景 | Natural cytotoxicity triggering receptor 3 (CD337/NCR3) is a ~21 kDa protein. Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation. |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |

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