Anti-Mouse CD282/TLR2 Recombinant Antibody (SAA1384), PE (MT188127)

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货号	MT188127
品牌	abinScience
种属反应性	Mouse
应用	FCM, IF, WB
宿主	Mouse
同种型	IgG2a, kappa
克隆号	SAA1384
偶联物	PE
克隆类型	Monoclonal
靶标	TIL4, Toll-like receptor 2, TLR2, Toll/interleukin-1 receptor-like protein 4, CD282
内毒素水平	Please contact with the lab for this information.
相关产品	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), PE
Accession号	Q9QUN7
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Toll-like receptor 2 (CD282/TLR2) is a ~89 kDa protein. Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. 1. Hoebe, K. et al. (2005) Nature 433, 523-7. PMID: 15690042 2. Pathak, SK. et al. (2007) Nature immunology 8, 610-8. PMID: 17486091 3. Drage, MG. et al. (2009) Cellular immunology 258, 29-37. PMID: 19362712 4. Chen, ST. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 188, 668-77. PMID: 22174456 5. Deboosère, N. et al. (2017) Cellular microbiology 19. PMID: 27220037
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

产品说明书

Anti-Mouse CD282/TLR2 Recombinant Antibody (SAA1384), PE.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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Anti-Mouse CD282/TLR2 Recombinant Antibody (SAA1384), PE (MT188127)

概述

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参考文献

产品说明书

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重组蛋白

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实验相关试剂

Anti-Mouse CD282/TLR2 Recombinant Antibody (SAA1384), PE (MT188127)

概述

图片

参考文献

产品说明书

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