

| 货号 | HY260127 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Human |
| 应用 | FCM |
| 宿主 | Human |
| 同种型 | IgG4, kappa |
| 克隆号 | SAA0058 |
| 偶联物 | PE |
| 克隆类型 | Monoclonal |
| 经测试应用 | FCM |
| 靶标 | Beta-type platelet-derived growth factor receptor, Beta platelet-derived growth factor receptor, CD140b, Platelet-derived growth factor receptor 1, PDGFRB, PDGF-R-beta, Platelet-derived growth factor receptor beta, CD140 antigen-like family member B, PDGFR-1, PDGFR1, PDGFR-beta, PDGFR |
| 内毒素水平 | Please contact with the lab for this information. |
| 相关产品 | Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4), PE |
| Accession号 | P09619 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 背景 | Platelet-derived growth factor receptor beta (CD140b/PDGFRB) is a ~123 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites. Required for normal development of the cardiovascular system. Required for normal recruitment of pericytes (mesangial cells) in the kidney glomerulus, and for normal formation of a branched network of capillaries in kidney glomeruli. |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |

Flow-cytometry using PE anti-human CD140b antibody. MG-63 cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an PE anti-human CD140b monoclonal antibody (Catalog: HY260127, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.



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