Anti-Human B7-2/CD86 Recombinant Antibody (SAA1397), PE (HW776227)

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货号	HW776227
品牌	abinScience
种属反应性	Human
应用	ELISA, FCM
宿主	Mouse
同种型	IgG2a, kappa
克隆号	SAA1397
偶联物	PE
克隆类型	Monoclonal
经测试应用	FCM
靶标	BU63, B70, CD28LG2, CTLA-4 counter-receptor B7.2, Activation B7-2 antigen, T-lymphocyte activation antigen CD86, CD86, FUN-1
内毒素水平	Please contact with the lab for this information.
相关产品	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), PE
Accession号	P42081
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	T-lymphocyte activation antigen CD86 (B7-2) is a ~37 kDa protein. Costimulatory molecule that belongs to the immunoglobulin superfamily that plays an important role in T-lymphocyte activation. Acts as the primary auxiliary signal augmenting the MHC/TCR signal in naive T-cells by acting as a ligand for the CD28 receptor which is constitutively expressed on the cell surface of T-cells. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Also involved in the regulation of B cells function, plays a role in regulating the level of IgG(1) produced. Upon CD40 engagement, activates NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation. 1. Collins, AV. et al. (2002) Immunity 17, 201-10. PMID: 12196291 2. Freeman, GJ. et al. (1993) Science (New York, N.Y.) 262, 909-11. PMID: 7694363 3. Lanier, LL. et al. (1995) Journal of immunology (Baltimore, Md. : 1950) 154, 97-105. PMID: 7527824 4. Schwartz, JC. et al. (2001) Nature 410, 604-8. PMID: 11279501
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

Flow CytoMetry

Flow-cytometry using PE anti-human CD86 antibody. Daudi cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human CD86 monoclonal antibody (Catalog: HW776227, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

产品说明书

Anti-Human B7-2/CD86 Recombinant Antibody (SAA1397), PE.pdf

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Anti-Human B7-2/CD86 Recombinant Antibody (SAA1397), PE (HW776227)

概述

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参考文献

产品说明书

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重组蛋白

抗体

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实验相关试剂

Anti-Human B7-2/CD86 Recombinant Antibody (SAA1397), PE (HW776227)

概述

图片

参考文献

产品说明书

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