Anti-Human LRRC32/GARP Recombinant Antibody (SAA0543), PE (HC573127)

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货号	HC573127
品牌	abinScience
种属反应性	Human
应用	ELISA, FCM
宿主	Mouse
同种型	IgG2a, kappa
克隆号	SAA0543
偶联物	PE
克隆类型	Monoclonal
靶标	GARP, Leucine-rich repeat-containing protein 32, Glycoprotein A repetitions predominant, D11S833E, Garpin, Transforming growth factor beta activator LRRC32, LRRC32
内毒素水平	Please contact with the lab for this information.
相关产品	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), PE
Accession号	Q14392
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Transforming growth factor beta activator LRRC32 (GARP) is a ~71 kDa protein. Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta. Able to outcompete LTBP1 for binding to LAP regulatory chain of TGF-beta. Controls activation of TGF-beta-1 (TGFB1) on the surface of activated regulatory T-cells (Tregs). Required for epithelial fusion during palate development by regulating activation of TGF-beta-3 (TGFB3). 1. Tran, DQ. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 13445-50. PMID: 19651619 2. Stockis, J. et al. (2009) European journal of immunology 39, 3315-22. PMID: 19750484 3. Wang, R. et al. (2012) Molecular biology of the cell 23, 1129-39. PMID: 22278742
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

产品说明书

Anti-Human LRRC32/GARP Recombinant Antibody (SAA0543), PE.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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C₁ × V₁ = C₂ × V₂

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Anti-Human LRRC32/GARP Recombinant Antibody (SAA0543), PE (HC573127)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

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实验相关试剂

Anti-Human LRRC32/GARP Recombinant Antibody (SAA0543), PE (HC573127)

概述

图片

参考文献

产品说明书

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