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Anti-Human IL-31RA Recombinant Antibody (SAA0825), PE (HV121127)

价格:
规格:
  • 50T
  • 100T
数量:
  • 概述

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  • 参考文献

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概述
货号HV121127
品牌abinScience
种属反应性Human
应用ELISA, FCM
宿主Human
同种型IgG2, kappa
克隆号SAA0825
偶联物PE
克隆类型Monoclonal
经测试应用FCM
靶标IL-31RA, Interleukin-31 receptor subunit alpha, IL31RA, hGLM-R, ZcytoR17, IL-31R-alpha, GPL, CRL3, Cytokine receptor-like 3, IL-31R subunit alpha, IL-31 receptor subunit alpha, Gp130-like receptor, GLM-R, Gp130-like monocyte receptor
内毒素水平Please contact with the lab for this information.
相关产品 Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10), PE
Accession号Q8NI17
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Store at 4°C for 12 months. Protect from light. Do not freeze.
背景

Interleukin-31 receptor subunit alpha (IL31RA) is a ~82 kDa protein. Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro.

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1. Ghilardi, N. et al. (2002) The Journal of biological chemistry 277, 16831-6. PMID: 11877449
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2. Diveu, C. et al. (2003) The Journal of biological chemistry 278, 49850-9. PMID: 14504285
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3. Dreuw, A. et al. (2004) The Journal of biological chemistry 279, 36112-20. PMID: 15194700
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4. Diveu, C. et al. (2004) European cytokine network 15, 291-302. PMID: 15627637
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5. Dillon, SR. et al. (2004) Nature immunology 5, 752-60. PMID: 15184896
NoteFor flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
图片
  • Flow CytoMetry

    Flow-cytometry using PE anti-human IL31RA antibody. U87 cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human IL31RA monoclonal antibody (Catalog: HV121127, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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