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Urelumab ELISA Kit (KPTX241)

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概述
货号KPTX241
品牌ProteoGenix
样本类型Plasma, Serum
检测范围31.25 - 2,000 ng/mL
保存溶液 When the kit was stored at the recommended temperature for 6 months, the signal intensity decreased by less than 20%. For unopened kits, if you want to prolong the storage time, please store the Standard, Detection A, Detection B and Microplate at - 20℃, the rest reagents should be store at 4℃.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

检测方法Colorimetric
实验类型Quantitative
回收率80-120%
运输2-8 ℃
规格Urelumab
别名BMS-663513, CAS: 934823-49-1
背景Urelumab is a fully humanized agonistic monoclonal antibody targeting the CD137 receptor with potential immunostimulatory and antineoplastic activities. Urelumab specifically binds to and activates CD137-expressing immune cells, stimulating an immune response, in particular a cytotoxic T cell response, against tumor cells. Urelumab has been used in trials studying the treatment of Leukemia, Multiple Myeloma, Malignant Tumors, and Cancer-Solid Tumors and B-Cell Non-Hodgkin's Lymphoma. The antibody product was developed using Medarex's UltiMAb(R) technology and was the first UltiMAb-derived antibody in clinical development by Bristol-Myers Squibb under the December 2003 agreement with Medarex. In December 2008, enrolment was stopped for all urelumab studies following the occurrence of two hepatotoxicity-related deaths. Several years later, the clinical study on Urelumab was restarted. At present, the approval of the monoclonal antibody has not been disclosed in the relevant drug approval agency.
NoteFor Research Use Only.
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