注册
CN
首页 > 产品中心 > 试剂盒 > ADA检测试剂盒

Lodelcizumab ELISA Kit (DV612058)

价格:
规格：
  • 96T
数量：
联系我们
一键复制产品信息

  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号DV612058
品牌abinScience
描述
Lodelcizumab ELISA Kit (DV612058) — Quantitative sandwich ELISA for Lodelcizumab. Sample: Plasma, Serum. Range: 0.31-5 μg/mL. Sensitivity: 0.156 μg/ml.
Highlights
  • ●Sandwich Format — High specificity, reliable quantification.
  • ●High Sensitivity — Optimized for low-abundance target detection.
  • ●Ready-to-Use — Complete kit with pre-coated plates included.
样本类型Plasma, Serum
灵敏度0.156 μg/ml
检测范围0.31-5 μg/mL
Accession号Q8NBP7
应用ELISA
检测方法Colorimetric
实验类型Quantitative
回收率80-120%
运输2-8 ℃
稳定性和存储The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
规格

Lodelcizumab

别名LGT209, NVP-LGT209, 1355338-54-3
背景

Proprotein convertase subtilisin/kexin type 9 (Lodelcizumab) is a ~74 kDa protein. Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments. Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway. May prevent the recycling of LDLR from endosomes to the cell surface or direct it to lysosomes for degradation. Can induce ubiquitination of LDLR leading to its subsequent degradation.

1. Poirier, S. et al. (2008) The Journal of biological chemistry 283, 2363-72. PMID: 18039658
2. Nassoury, N. et al. (2007) Traffic (Copenhagen, Denmark) 8, 718-32. PMID: 17461796
3. Fan, D. et al. (2008) Biochemistry 47, 1631-9. PMID: 18197702
4. Mayer, G. et al. (2008) The Journal of biological chemistry 283, 31791-801. PMID: 18799458
5. Chen, Y. et al. (2011) Biochemical and biophysical research communications 415, 515-8. PMID: 22074827
6. Jonas, MC. et al. (2008) EMBO reports 9, 916-22. PMID: 18660751
NoteFor Research Use Only.
图片

  • Standard Curve

    Standard Curve of Lodelcizumab ELISA Kit

参考文献
产品说明书
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

相关产品推荐

获取报价

Lodelcizumab ELISA Kit

  • 7X24小时产品咨询热线：027--87433958(9:00-18:00)，或扫描下方产品专员二维码或在线留言

  • 武汉东湖新技术开发区神墩四路666号研发楼B区3层东

  • 24小时产品查询

    24小时产品查询

  • 24小时产品查询

    扫一扫关注我们

  • 24小时产品查询

    专属渠道经理

Copyright © 2026 武汉艾必赛生物科技有限公司版权所有 所有产品仅可用于工业或者科研等非医疗目的。
鄂ICP备2023002448号-2