

| 货号 | AB691018 |
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| 品牌 | abinScience |
| 描述 | _x005F_x000d_
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Anti-Daratumumab ELISA Kit (AB691018) — Quantitative sandwich ELISA for Anti-Daratumumab. Sample: Plasma, Serum. Range: 156.25 - 10, 000 ng/mL. _x005F_x000d_
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| 样本类型 | Serum, plasma, and other biological fluid samples |
| 灵敏度 | 0.61 ng/mL |
| 检测范围 | 1.56 - 100 ng/mL |
| 种属反应性 | Human |
| 靶标 | CD38/ADPRC 1 |
| Accession号 | P28907 |
| 应用 | ELISA |
| 检测方法 | Colorimetric |
| 实验类型 | Sandwich |
| 回收率 | 80-120% |
| 运输 | 2-8 ℃ |
| 稳定性和存储 | The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition. |
| 规格 | Daratumumab _x005F_x000d_ |
| 别名 | 945721-28-8 |
| 背景 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (Daratumumab) is a ~34 kDa protein. Multifunctional transmembrane glycoprotein able to exert enzymatic activities and also to mobilize calcium, to transduce signals, to adhere to hyaluronan and to other ligands. Synthesizes cyclic ADP-ribose (cADPR), a second messenger for glucose-induced insulin secretion. Synthesizes the Ca(2+) mobilizer nicotinate-adenine dinucleotide phosphate, NAADP(+), from 2'-phospho-cADPR and nicotinic acid, as well as from NADP(+) and nicotinic acid. At both pH 5.0 and pH 7.4 preferentially transforms 2'-phospho-cADPR into NAADP(+), while preferentially cleaving NADP(+) to cADPR and ADPRP rather than into NADDP(+). Has cADPR hydrolase activity. _x005F_x000d_ _x005F_x000d_1. Tohgo, A. et al. (1994) The Journal of biological chemistry 269, 28555-7. PMID: 7961800 _x005F_x000d_
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2. Takasawa, S. et al. (1993) The Journal of biological chemistry 268, 26052-4. PMID: 8253715 _x005F_x000d_
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3. Moreschi, I. et al. (2006) Biochemical and biophysical research communications 345, 573-80. PMID: 16690024 _x005F_x000d_
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4. Deaglio, S. et al. (1998) Journal of immunology (Baltimore, Md. : 1950) 160, 395-402. PMID: 9551996 _x005F_x000d_
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5. Frasca, L. et al. (2006) Blood 107, 2392-9. PMID: 16293598 _x005F_x000d_
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6. Deaglio, S. et al. (2001) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 15, 580-2. PMID: 11259373 _x005F_x000d_ |
| Note | For Research Use Only. |

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