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Anti-Atezolizumab ELISA Kit (AV974018)

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  • 96T
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概述
货号AV974018
品牌abinScience
描述
Anti-Atezolizumab ELISA Kit (AV974018) — Quantitative sandwich ELISA for Anti-Atezolizumab. Sample: Plasma, Serum. Range: 156.25 - 10, 000 ng/mL.
Highlights
  • ●Sandwich Format — High specificity, reliable quantification.
  • ●Ready-to-Use — Complete kit with pre-coated plates included.
样本类型Plasma, Serum
检测范围156.25 - 10, 000 ng/mL
Accession号Q9NZQ7
应用ELISA
检测方法Colorimetric
实验类型Quantitative
回收率80-120%
运输2-8 ℃
稳定性和存储The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
规格

Atezolizumab

别名MPDL3280A, RG7446, 1380723-44-3
背景

Programmed cell death 1 ligand 1 (Atezolizumab) is a ~33 kDa protein. Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response. Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10). Can also act as a transcription coactivator: in response to hypoxia, translocates into the nucleus via its interaction with phosphorylated STAT3 and promotes transcription of GSDMC, leading to pyroptosis.

1. Freeman, GJ. et al. (2000) The Journal of experimental medicine 192, 1027-34. PMID: 11015443
2. Mezzadra, R. et al. (2017) Nature 549, 106-110. PMID: 28813410
3. Burr, ML. et al. (2017) Nature 549, 101-105. PMID: 28813417
4. Huang, X. et al. (2019) Cancer immunology research 7, 1580-1590. PMID: 31399419
5. Kennedy, A. et al. (2023) The EMBO journal 42, e111556. PMID: 36727298
6. Dong, H. et al. (1999) Nature medicine 5, 1365-9. PMID: 10581077
7. Hou, J. et al. (2020) Nature cell biology 22, 1264-1275. PMID: 32929201
NoteFor Research Use Only.
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参考文献
产品说明书
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Atezolizumab ELISA Kit

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