货号 | DY353048 |
---|---|
品牌 | abinScience |
样本类型 | Plasma, Serum |
灵敏度 | 0.156 μg/ml |
检测范围 | 0.31-5 μg/mL |
Accession号 | P08069 |
应用 | ELISA |
检测方法 | Colorimetric |
实验类型 | Quantitative |
回收率 | 80-120% |
运输 | 2-8 ℃ |
稳定性和存储 | The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition. |
规格 | Ganitumab |
别名 | AMG 479, CAS: 905703-97-1 |
背景 | Ganitumab (AMG-479) is a mAb against IGF-IR which also inhibits binding of both IGF-1 and IGF-2 ligands to IGF-IR. The therapeutic value of AMG-479 was evaluated in several preclinical settings including androgen-dependent prostate cancer, and combined with androgen-deprivation therapy. Ganitumab was found to be most potent against VCaP xenografts when it was used in combination with complete androgen-deprivation therapy. After 4 weeks of treatment, tumor volume was reduced by 72% and growth suppression was maintained over 16 weeks of treatment. These findings suggested that the use of ganitumab in conjunction with androgen-deprivation therapy may be beneficial in the treatment of prostate cancer. |
Note | For Research Use Only. |
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